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ISO 11161:2007 specifies the safety requirements for integrated manufacturing systems (IMS) that incorporate two or more interconnected machines for specific applications, such as component manufacturing or assembly. It gives requirements and recommendations for the safe design, safeguarding and information for the use of such IMSs. ISO 11161:2007 is not intended to cover safety aspects of individual machines and equipment that may be covered by standards specific to those machines and equipment. Therefore it deals only with those safety aspects that are important for the safety-relevant interconnection of the machines and components. Where machines and equipment of an integrated manufacturing system are operated separately or individually, and while the protective effects of the safeguards provided for production mode are muted or suspended, the relevant safety standards for these machines and equipment apply.

ISO 12100:2010 specifies basic terminology, principles and a methodology for achieving safety in the design of machinery. It specifies principles of risk assessment and risk reduction to help designers in achieving this objective. These principles are based on knowledge and experience of the design, use, incidents, accidents and risks associated with machinery. Procedures are described for identifying hazards and estimating and evaluating risks during relevant phases of the machine life cycle, and for the elimination of hazards or sufficient risk reduction. Guidance is given on the documentation and verification of the risk assessment and risk reduction process. ISO 12100:2010 is also intended to be used as a basis for the preparation of type-B or type-C safety standards. It does not deal with risk and/or damage to domestic animals, property or the environment.